Pass-through disks are disappearing after configuring MPIO on Windows VM along with Virtual Fiber Channel

I have a Windows 2016 Server (Base System) with Hyper-V enabled with a Windows 2016 VM (Win-VM).

Disks are presented from various Target Arrays to Base System and MPIO is configured. Each disks having four physical paths. Few disks are attached as pass-through disks to Win-VM.  And these disks are visible in the Win-VM.

Now I have created two Virtual Fiber Channel (Two Physical port in each VFC) and presented disks from same Target arrays. ThenI have configured MPIO in guest VMs (Win-VM) also.

Here starts my problem.

After configuring MPIO in guest VM that is in my case Win-VM, few pass-through disks are disappearing fromWin-VM.

I have two questions.

1.       Whether the above scenario is a valid configuration? (Can we use Pass-through disks and VFC disks in same system)
2.       If it is a valid configuration, why pass-through disks are disappearing?