For a customer we have a MAIN/DR solution based on Hyper-V and Replicas.
Main is equipped with 2 x Windows 2012 in a cluster, DR has one host standalone with Hyper-V.
The whole shebang is managed via SCVMM 2012 and we have replication enabled for around 4 VM's going from MAIN to DR.
Everything is working ok for a while and then all of a sudden we're getting events in our NOC about the fact that the replication has stopped. Upon further investigation we found a couple of events stating:
"Hyper-V failed to open the file 'C:\ClusterStorage\Volume1\VP-SCSQL01\VP-SCSQL01_E.vhdx' for replication in primary server for virtual machine 'VP-SCSQL01': General access denied error (0x80070005). (Virtual Machine ID B7020EE9-A781-4F50-B387-E781FC7F2315)"
When we recreate the replication (so really deleting everything and setting the VM replication up from scratch) it starts and works fine. Resuming replication does not work.